ח יסוני ילדים במאה ה- 21 יעילות , בטיחות והטענות שכנגד

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  • - 21 , ' ' '

    ' 2004

  • 10 ' 1999-1990 (JAMA, 2000) ()

  • 1992- 2002 - - 40% B A- Hib = B ( ) : DOTS

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  • "" (1)1. 2. 3. 120 -19 !!

    123

  • "" (2)1. , , 2.

    12

  • ', : 1. A 2. -Hib

  • ' ,

  • Comparison of Maximum and Current Morbidity Vaccine Preventable Diseases-- Nationwide

    1 Estimated2 Mortality3 Preliminary Data

    (Data Source: MMWR-2001)

    Maximum Cases

    20013

    Percent Change

    Diphtheria

    Measles

    Mumps

    Pertussis

    Polio (paralytic)

    Rubella

    CRS

    Smallpox

    Tetanus

    H. influenzae, invasive (

  • Control of Polio in the U.S. ( ) ,

  • Polio in Israel, 1950-2003 ( )IPV, 1957OPV, 1961 - 50

  • Diphtheria in Israel, 1950-69 ( )Vaccine, 1951

  • ')) Reported Measles Cases U.S.A. - CDC vaccine

  • Measles in Israel 1950-2003 ()Vaccine - 700,000

    -2003 60

  • Pertussis in Israel1950-2003 ()Vaccine, 1957

  • Tetanus in Israel 1950-2003( )Vaccine, 1955

  • MMR1MMR2 2

  • .....

  • Vaccine licensed, 1992Vaccine routine, 1994Improved living standards - 100 , -5

  • Vaccine, 1.7.99Improving Sanitation > 90%

  • : : - (: ) ( )

  • "": (1): , ... : , ,

  • "": (2): : , -, , , , , , , , (LUPUS) (MS)

    :

  • "":: B , ?: - 2%-1 (- 2,000 ) B - 140,000 ,

  • - " ( -) - 50, , - HIb -100 - 2-4 1994 A ( 96% 3 !!)

  • , : ! ?

  • 1-4 , 2001 : 2 : 75,314/ 4-1: 32,606/ ( - 1000 ) 2000 14 : 5.64-1: 0.4 : 2.2 : 6.5 4-1: 2.9 4-1: 0.3

  • (Whole cell) - 1974 - DTP (- 70%), : - 1978 102,500 - 36 - National Childhood Encephalopathy Study

  • ? (1): 30 , : ,

  • (2) 2002 New England Journal of Medicine 1998-1991 440,655 MMR (82%), 96,648 " 316 , - 422 : 0.92 : 0.83

  • (3)

    , .....

    Et al, BMJ. 2001 Feb 24;322(7284):460-3., ickHCONCLUSIONS: Because the incidence of autism among 2 to 5 year olds increased markedly among boys born in each year separately from 1988 to 1993 while MMR vaccine coverage was over 95% for successive annual birth cohorts, the data provide evidence that no correlation exists between the prevalence of MMR vaccination and the rapid increase in the risk of autism over time. The explanation for the marked increase in risk of the diagnosis of autism in the past decade remains uncertain. Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis

  • WAKEFIELD "" Wakefield ' - Lancet , MMR . - 18 2004 Lancet . Wakefield , . Wakefield

  • : / ? .....

    ,

  • : - 100,000 : , , - , - ( ' 2003)

  • Dysentery in U.S., 1955-93: No Effect of Improved Hygiene

  • Typhoid Fever in the U.S., 1971-2001:Effect of Improved Sanitation ?

  • Meningococcal Disease in the U.S., 1955-93: Effect of Improved Nutrition & Less Crowding

  • MMMMR- 1985 , . - 8 1987 , .

  • 700,000 (AIDS), BAVARIA 2002: 1,000 76% - 2003

  • COMMUNITY (HERD) IMMUNITY " " 90%

  • " " "" , : , : , , , , ( ...) - 2002 - 2003

  • (1) " " Moral Imperative A Human right"

  • (2) ? - : " ", " "

  • , , ! , ' : ".... "FEVER IS NOT A CEFUROXINE DEFICIENCY STATE"

  • : , / / 1

  • ' 2004