Распределение 239Pu в организме человека

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<ul><li><p>" ", 1995, .5 </p><p>61 </p><p> " ", 1965 , 1, . 9-16. </p><p> 239Pu </p><p> .. </p><p> 34 -, , , - - . - ( ); - ; - . : ; - - . </p><p>Biodistribution of 239</p><p>Pu </p><p>Plotnikova A.A. </p><p>A radiometric study of organs and tissues by 34 workers involved into plutonium production and died due to different reasons showed that distribution of plutonium in human organism by its in-halation depends on physico-chemical properties of isotope compounds. By transfer of soluble compounds it deposits to a greater degree in skeleton and to a less degree - in liver and lungs, by transfer of insoluble compounds - in lungs. By solubility of different degree the distribution is of mixed type. Distribution of plutonium in lungs is irregular: maximum isotope concentration is observed in superior lobes or lymphoid, that one in skeleton - in thoracic vertebrae and cra-nium. </p><p> 34 , - ( ). - . I 15 , </p><p> . II (12 ), </p><p> , . - . III 7 , -</p><p> . </p><p> - - 4-11 , 3 . -</p><p> . -</p><p> - - [1]. - . , </p><p> 1, , . </p><p> 1 ( </p><p> ) I, II III </p><p>I </p><p>, </p><p>1 2 3 4 5 </p><p> t1=6 3 </p><p>t2=0 </p><p>t1=4 t2=7 </p><p>t1=4 t2=7 </p><p>t1=7 t2=0 </p><p>t1=4 t2=4 4 </p><p> 50,65,9 16,02,7 12,31,78 0,40,28 18,33,8 6,41,0 21,03,2 26,73,7 0 70,09,9 42,58,1 62,013,0 60,014,1 86,031,0 11,76,7 0,10,04 1,00,26 1,00,25 13,68,7 0 </p></li><li><p>" ", 1995, .5 </p><p>62 </p><p>, </p><p>6 7 8 9 10 </p><p> t1=3 5 t2=46 </p><p>t1=6 t2=5 </p><p>t1=3 t2=5 </p><p>t1=1 t2=0 </p><p>t1=7 t2=2 </p><p> 20,63,8 35,714,6 4,70,99 9,81,9 7,713,53 28,95,1 40,016,0 95,313,4 1,80,63 74,529,9 50,616,7 24,08,0 0 69,027,6 17,735,0 0 0,30,15 0 19,311,68 0 </p><p>, </p><p>11 12 13 14 15 </p><p> t1=4 </p><p>7 t2=7 </p><p>10 </p><p>t1=11 t2=10 </p><p>t1=2 2 t2=10 </p><p>7 </p><p>t1=5 5 </p><p>t2=0 </p><p>t1=11 3 </p><p>t2=1 </p><p> 1,40,6 29,45,6 2,51,2 45,26,8 11,53,0 13,82,3 70,612,4 49,39,4 10,12,5 24,22,5 80,635,4 0 48,225,1 44,727,3 62,214,0 4,21,28 0 0 0 0,90,3 </p><p>II </p><p>, </p><p>16 17 18 19 20 21 </p><p> t1=6 </p><p>11 t2=5 </p><p>2 </p><p>t1=5 3 t2=3 2 </p><p>t1=7 10 </p><p>t2=4 8 </p><p>t1=10 6 t2=2 </p><p>5 </p><p>t1=11 t2=2 </p><p>7 </p><p>t1=4 t2=2 </p><p>7 </p><p> 4,50,5 20,42,3 33,413,9 25,53,1 7,20,9 67,07,5 13,761,5 50,95,7 15,921,7 23,62,8 28,53,3 14,11,7 77,49,3 28,03,6 47,226,2 27,444,3 55,19,4 16,82,9 3,340,62 0,860,11 3,420,5 23,443,3 9,21,74 1,970,9 </p><p>, </p><p>22 23 24 25 26 27 </p><p> t1=8 </p><p>3 t2=4 -</p><p>t1=3 11 </p><p>t2=1 3 </p><p>t1=10 4 t2=3 </p><p>t1=7 9 t2=3 </p><p>t1=2 t2=0 </p><p>t1=8 t2=5 </p><p> 33,83,8 58,576,5 10,91,44 3,70,6 59,57,8 14,02,3 42,04,9 16,82,2 42,25,3 7,41,1 34,84,9 19,83,5 23,644,5 23,85,5 40,420,6 88,814,4 4,681,7 64,717,3 0,550,16 1,130,2 6,53,2 0,110,033 1,020,48 1,50,5 </p><p>III </p><p>, </p><p>28 29 30 t1=4 11 </p><p>t2=0 t1=7 3 </p><p>t2= 1 6 t1=6 7 t2=1 3 </p><p> 90,511,4 90,813,6 95,316,9 9,41,6 8,61,6 4,50,95 0 0 0 0,10,06 0,60,094 0,20,155 </p></li><li><p>" ", 1995, .5 </p><p>63 </p><p>, </p><p>31 32 33 34 </p><p> t1=8 </p><p>10 t2=1 </p><p>6 </p><p>t1=4 t2=0 </p><p>t1=2 6 </p><p>t2=6 </p><p>t1=1 t2=0 </p><p> 79,710,7 65,79,4 83,512,0 93,714,5 8,31,7 15,12,9 12,43,8 6,33,5 2,21,2 19,29,0 0 0 0 0 4,12 0 </p><p> . t1 - ; t2 - , . I ( 9 15 ) </p><p> -, 42,5-86% - . (70-95 %) - (45,2 50,6 %). , , , , , -, , - , - . II </p><p> , - , - . - - ( 16, 18, 19, 20, 25, 27) ( 17, 22, 23), -</p><p> - ( 21, 23). - , .. [2], -. ( 26), , - . ( , I - 1 14) - . , -</p><p> - -, . - ( .. ..) I II (. 2). </p><p> 2 </p><p> , </p><p> - </p><p> (r) </p><p> (p) t1 t2 t1+ t2 t1 t2 t1+ t2 t1 t2 t1+ t2 </p><p>I (23) r -0,13 -0,59 -0,54 +0,2 -0,2 -0,2 +0,2 +0,32 +0,3 p &gt;0,1 0,1 &gt;0,1 &gt;0,1 &gt;0,1 &gt;0,1 II (10) r -0,62 -0,63 -0,77 -0,14 -0,51 -0,13 +0,37 +0,68 +0,60 p 0,1 &gt;0,1 </p></li><li><p>" ", 1995, .5 </p><p>64 </p><p> , -, - - - , , . - [3-6]. -</p><p> . I -</p><p> , -. , , 5-8 . </p><p> II , - - - , . III -</p><p>, 8-10 . -</p><p> -, . - II . - ( - , ) 1. </p><p>. 1. ( % (1), (2) </p><p> (3) ): , , , , - 20, 33, 16, 18, 19. </p></li><li><p>" ", 1995, .5 </p><p>65 </p><p> , , - . [6], -, - . -, - - , - , - [4, 5], . , , , (p</p></li><li><p>" ", 1995, .5 </p><p>66 </p><p> - - , , -, --. </p><p> (. 3). . , I, II III . -</p><p> I - 0,02 0,09 %, 0,05 % . ( .. .. ). 4-7 . -, , - . </p><p> 3 </p><p> I, II III </p><p> , / </p><p> , % -</p><p> - </p><p>, </p><p> 4 50(2) 60(2) 0,024 0,035 1 2 110(3) 110(3) 0,087 0,087 2 3 2 0(3) 0(3) - - 3 10 0(3) 0(3) - - 5 0(40) 0(10) - - 0,0550,003 0,0610,025 I 4 350(1) - 0,050 - 11 1 11 100(1) - 0,030 - 7 8 0(4) - 0 - 0,040,008 - 9 6 0(4) 0(2) - - 13 11 6 0(3) 0(3) - - </p><p> 0,0480,006 - </p><p> 2 3 470(3) 900(2) 0,003 0,005 16 3 4 970(2) 620(2) 0,006 0,004 4 3 230(5) 450(4) 0,001 0,003 5 380(6) 120(2) 0,002 0,001 0,0030,001 0,0030,0009 17 2 1030(3) 1020(1) 0,006 0,006 18 1 2 300(1) 750(1) 0,003 0,006 1 4 380(1) - 0,003 - 1 8 210(1) - 0,002 - 1 11 960(4) 200(4) 0,009 0,002 4 6 530(29) 400(28) 0,004 0,004 </p><p>II 0,0040,001 0,0040,001 6 130(9) 140(6) 0,002 0,002 19 1 3 220(7) 120(6) 0,003 0,002 1 4 110(3) 70(3) 0,001 0,001 1 10 190(16) 160(10) 0,003 0,002 0,0020,0006 0,0020,0003 20 2 290(3) 80(3) 0,008 0,002 2 8 280(3) 170(3) 0,010 0,007 0,0090,001 0,00450,0025 21 1 20(40) 60(40) 0,0015 0,0044 </p><p> 0,00450,00115 0,0040,0005 </p><p> 29 10 0(20) 0(20) - - 2 0(10) 0(8) - - </p><p>III 2 7 0(19) 0(10) - - 30 3 0(5) 0(3) - - 1 1 0(3) 0(2) - - 1 6 0(2) 0(1) - - </p><p> . . </p></li><li><p>" ", 1995, .5 </p><p>67 </p><p> II 0,0045 0,004 % -. , - , I , - . III 3-10 -</p><p> - , . </p><p> , - 20 , . - . </p><p> , -, - , -, - . - - [10, 14], . </p><p>1. , , - . </p><p>2. , , , - . </p><p>3. : - , - , - . </p><p>4. , -, - . </p><p>5. -: </p><p> - . </p><p>6. - : , - . </p><p>7. - , - . </p><p>1. C.. - . ., 1957. </p><p>2. .. -, -. , 1961, N 2, . 82. </p><p>3. Scott K, Axelrod A.D. and oth. Arch. Pathol., 1949, 48, 1, p. 31. </p><p>4. Bair W.J., Willard D.H. and oth. Health Phys., 1962, 8, 6, p. 639. </p><p>5. Bair W.J., Mc Clanhan B.J. Health Phys., 1961, 2, 6, p. 648. </p><p>6. Langham W.H., Laurence J.N. Health Phys., 1962, 8, 6, p. 753. </p><p>7. ., ., . - . , 1957, . 600. </p><p>8. .. . ., , 1960. </p><p>9. Ball W.C., Stewart P.B. a. oth. J. Clin. Investig., 1961, 41, 3, p. 519. </p><p>10. .., .. - -. . "-239". . . - ... ., , 1962. </p><p>11. .. - . ., , 1963. </p><p>12. .., .. . ., 1948. </p><p>13. .. . ., , 1959, . 121. </p><p>14. Stover B.J., Atherton D.R. and Keller N. Rad. Res., 1959, 10, p. 130. </p></li></ul>

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