Анализ опубликованных последовательностей SOIV (апрель-май 2009 г.)

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SOIV (- 2009 .). 05.05.2009 20:00 . 1490 21 57 11 22 9 7 4 4 4. - 3 - PowerPoint PPT Presentation

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  • SOIV (- 2009 .)

  • 05.05.2009 20:00 1490 21 57 11 22 9 7 4 4 4 - 3 1 1 1 1

  • :A/California/04/2009 ( 01.04.2009)A/California/06/2009 ( 16.04.2009)A/Mexico/4604/2009 ( 19.04.2009)A/New York/18/2009 ( 25.04.2009)A/Canada-ON/RV1527/2009A/Mexico/InDRE4487/2009

  • HA 98,8% : L32I ( ), S83P ( ), S203T ( -).

  • HA (95%) A/swine/Indiana/P12439/00 (H1N2) ( 1999 .) - - 26 A/Wisconsin/10/1998 (H1N1) (92%) ( (PB1) (PB2, PA)) 20 ( )

    ( Olsen, 2002)

  • A/Brisbane(H1N1)- /Brisbane/59/2007 (H1N1), , 79% 103 >30 >20 1 .. (K) 129 130 /Brisbane/59/2007 276

  • A/swine/New Jersey/11/76 HA /California/04/09 /Texas/05/09 HA A/swine/New Jersey/11/76, 90% 35 14

  • NA 94,2% : S95G (A/California/06/2009), V106I, N248D ( - ).

  • NA (94%) A/Swine/England/195852/92 (H1N1) . N1 (avian-like)A/Thailand/271/2005 (H1N1) (90%) 4- (, , ). , NS ( ).

  • A/Brisbane(H1N1)- /Brisbane/59/2007 (H1N1), , 77,3% 87 1 .. T436del A/Brisbane/59/2007

  • Reid A. H., Fanning T. G., Janczewski T. A. Taubenberger J. K. Characterization of the 1918 Spanish influenza virus neuraminidase gene // Proc. Natl. Acad. Sci. USA. 2000. Vol. 97. P. 6785-6790

    Strain7477798184188264267285287307344352

    AvianF/LEAATIVVAENYKSw/Eng/92FETVKIVVSENNKBrevig/18VGDTIMTITKDNRHuman, oldVGDTIMTITKDNRSwine, oldIGDTIMIITKDNRHuman, newVGDTTMTITTNDRSwine, newIGDTIMIITKDNR

    SOIV 2009FGSVKIVVSENNK

    Location:StStStStSISSSISIS