Παιδιατρική | Τόμος 71 • Τεύχος 1 • Ιανουάριος - Φεβρουάριος 2008

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    e-mail: hps@ath.forthnet.gr

    :http://www.e-child.gr/Instructions_to_Authors_GR.pdf

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    210 7771 663Fax: 210 7758 354e-mail: hps@ath.forthnet.gr

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    1 New Methods and Trends in PaediatricEducation. Undergraduate TrainingK. Sostmann, J. Hoeffe, S. Mueller, H. Krude, G. Gaedicke

    5 : . . , . , . , .

    14 . , .

    21 : . , . , .

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    38 MMEECCPP22 . , J. Traeger-Synodinos, . , . -, . , . , .

    48 . , . , . , . , . , . , . . , . , . , .

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    62 : - . .

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    , 2007E.

    83

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    71 1 - 2008

    : 3889

    ISSN 0377-2551

    Pediatri Jan-Feb 08 15-02-08 10:59 1

  • Bimonthly Publication ofthe Greek Paediatric Society

    PresidentA. Constantopoulos

    Editorial Board

    Editor-in-ChiefC. Stefanidis

    MembersS. AndronikouP. Augoustides-SavvopoulouA. Vazeou-GerasimidiG. Varlamis. GalanakisL. ThomaidouM. Kanariou. Katsarou-PectasidesA. KattamisS. Kitsiou-Tzeli. PapadopoulouN. PapadopoulosA. Siamopoulou-Mavridou M. Tsolia

    Manuscript submission

    e-mail: hps@ath.forthnet.gr

    Instructions to authors:http://www.e-child.gr/paediatriki/iae.pdf

    Manuscript Editing

    Greek EditingM. Natsoulidou

    English EditingS. Nakou

    Publisher

    K. Griveas

    Publishing Coordinator

    SCIENTIFIC PUBLICATIONS Ltd1 Pierias St. GR - 144 51, MetamorfossiTel.: +30 210 87 78 810 Fax: +30 210 87 78 822

    Owner

    Greek Paediatric Society

    92 Michalakopoulou St.GR - 115 28, AthensTel.: +30 210 7771 140

    +30 210 7771 663Fax: +30 210 7758 354e-mail: hps@ath.forthnet.gr

    Annual SubscriptionAll foreign countries: US $ 50

    ContentsEDITORIAL COMMENTARY

    xviii C. Stefanidis

    REVIEW ARTICLES

    1 New Methods and Trends in PaediatricEducation. Undergraduate TrainingK. Sostmann, J. Hoeffe, S. Mueller, H. Krude, G. Gaedicke

    5 Children with frequent infections: criteriafor specialized immunologicalinvestigationsD. C. Cassimos, . Liatsis, . Stogiannidou, . nariou

    14 Primary ciliary dyskinesia. oustaki, . Fretzayas

    21 Necrotizing enterocolitis: recent evidenceon the pathophysiology of the diseaseC. Tsakalidis, . Tragiannidis, . Nikolaidis

    29 Rheumatic fever: it is still here!C. Trapali, . Papafylaktou, G. Papadopoulos

    AWARD-WINNING ARTICLE

    38 Clinical studies and analysis of the MMEECCPP22gene in children with mental retardation inthe Greek populationS. Psoni, J. Traeger-Synodinos, C. Sofokleous, S. Kitsiou-Tzeli, . avrou, . anavakis, H. Fryssira

    ORIGINAL ARTICLES

    48 Sleep problems in school-age childrenJ. Kaleyias, V. Rouli, . Karatzaferi, . Dakoronias,. Papaioannou, T. Danidi, U. D. Papageorgiou,. Papoutsi, G. rokidas, . Diamantopoulos

    55 The impact of influenza in children on thecommunity. solia, . Logotheti, . Papadopoulos, . Mavrikou, . Spyridis, P. Drossatou, D. Kafetzis, . Konstantopoulos and theoutpatient flu study group

    PRACTICAL ISSUES

    62 Syncopal episodes in childhood andadolescence: diagnosis - managementD. I. Georgakopoulos

    CASE REPORTS

    68 An infant with eosinophilic enteritisC. outsaftiki, . Mantziou, D. Hatzis, . Papantzimas, . Stefanaki, . yriokefalitakis,. Roma-Giannikou

    74 Rhabdomyolysis following influenza Ainfection. Filippou, . Dolianiti, . Digalaki-Themeli, . Ziva-Petropoulou, S. Papadakou-Lagogianni

    79 CLINICAL QUIZ

    . Savvidou, G. Briassoulis, . Raisaki, A. . Spanaki, . Fytrolaki, . Galanakis, . Kalmandi

    80 PAEDIATRIC NEWS IN BRIEF

    Greek paediatric research in internationaljournals, 2007E. Galanakis

    83 NEWS FROM THE INTERNET

    C. Skevaki

    PaediatrikiVolume 71 Number 1 January-February 2008

    Pediatri Jan-Feb 08 15-02-08 10:59 3

  • v E EDITORIAL BOARD

    Members of the International Editorial Board

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    Editor-in-Chief

    Constantinos Stefanidis, Athens

    Section Editors

    Stella Andronikou, Neonatology, Ioannina

    Persefoni Avgoustides-Savvopoulou, Metabolic Disorders, Thessaloniki

    Andriani Vazaiou-Gerasimidi, Endocrinology, Athens

    George Varlamis, Cardiology, Thessaloniki

    Emmanouil Galanakis, Ethics and Deontology, Heraklion

    Loretta Thomaidou, Developmental Pediatrics, Athens

    Maria Kanariou, Immunology, Athens

    Eustathia Katsarou-Pektasides, Neurology, Athens

    Antonis Kattamis, Haematology - ncology, Athens

    Sophia Kitsiou-Tzeli, Genetics, Athens

    Alexandra Papadopoulou, Gastroenterology - Nutrition, Athens

    Nicos Papadopoulos, Allergology - Pneumonology, Athens

    Antigoni Siamopoulou-Mavridou, Rheumatology, Ioannina

    Marisa Tsolia, Infectious Diseases, Athens

    Alexis Arzimanoglou, Paris, France

    Ellis D. Avner, Milwaukee, USA

    Swati Bhave, New Delhi, India

    Alberto Bissot, Panama, Panama

    David Branski, Jerusalem, Israel

    Francesco Chiarelli, Chieti, Italy

    Chok-Wan Chan, Hong Kong, China

    Denis Daneman, Toronto, Canada

    Jochen Ehrich, Hannover, Germany

    Demetrius Ellis, Pittsburgh, USA

    Yoshikatsu Eto, Tokyo, Japan

    Richard N. Fine, Stony Brook, USA

    Margaret C. Fisher, Philadelphia, USA

    Raif Geha, Boston, USA

    Adenike Grange, Lagos, Nigeria

    Judith G. Hall, Vancouver, Canada

    Patricia Hamilton, London, UK

    Enver Hasanoglu, Ankara, Turkey

    Christer Holmberg, Helsinki, Finland

    Peter Hoyer, Essen, Germany

    Jan Janda, Prague, Czech Republic

    Jan Kimpen, Ultrecht, Netherlands

    Craig B. Langman, Chicago, USA

    John Manis, Boston, USA

    Manuel Moya, Alicante, Spain

    Hugh O'Brodovich, Toronto, Canada

    Ross Petty, Vancouver, Canada

    Willem Proesmans, Leuven, Belgium

    Jose Ramet, Antwerp, Belgium

    Alan Sinaiko, Minneapolis, USA

    Nick J. Spencer, Coventry, UK

    Alfred Tenore, Udine, Italy

    Alkis Togias, Bethesda, USA

    Eva Tsalikian, Iowa City, USA

    Catherine Weil-Olivier, Paris, France

    Max Zach, Graz, Austria

    Zheng-Yan Zhao, Hangzhou, China

    Johannes Zschocke, Heidelberg, Germany

    Pediatri Jan-Feb 08 15-02-08 10:59 5

  • xi

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    I. O

    A , , , - et al .

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    - . 1999;59:272-279.

    Proesmans W. Bartter syndrome and its neonatal variant. EurJ Pediatr 1997;156:669-679.

    :Flyvbjerg A. Role of growth hormone, insulin-like growth fac-

    tors (IGFs) and IGF-binding proteins in the renal complications ofdiabetes. Kidney Int 1997;52 (60 Suppl):S12-S19.

    :National Institutes of Health Consensus Development

    Conference. Neurofibromatosis conference statement. ArchNeurol 1988;45:575-578.

    :Schreiner GF, Lange L. Ethanol modulation of macrophage

    influx in glomerulonephritis [Abstract]. J Am Soc Nephrol1991;2:562.

    Should antileukotriene therapies be used instead of inhaledcorticosteroids in asthma? [Editorial]. Am J Respir Crit Care Med1998;158:1697-1701.

    Laux-End R, Inaebnit D, Gerber HA, Bianchetti MG. Vasculi-tis associated with levamisole and circulating autoantibodies [Let-ter]. Arch Dis Child 1996;75:355-356.

    II. :

    Clark AG, Barratt TM. Steroid-responsive nephrotic syn-drome. In: Barratt TM, Arner ED, Harmon WE, editors. PediatricNephrology. 4th ed. Baltimore: Lippincott William Wilkins; 1999.p. 742.

    :Gorlin RJ, Cohen MM, Levin LS. Syndromes of the head and

    neck. 3rd ed. New York: Oxford University Press; 1990.

    :Bauer AW. The two definitions of bacterial resistance. In:

    Smith AJ, Rogers CA, eds. Proceedings of the Third InternationalCongress of Chemotherapy; 1962 May 29-31; New York: Interna-tional Society of Chemotherapy; 1963. p. 484-500.

    : . [-

    ]. : ; 1979. Kaplan SJ. Post hospital home health care: the elderlys access

    and utilization [dissertation]. St. Louis (Mo): Washington Univ.;1995.

    . CD-ROMAnderson SC, Poulsen KB. Andersons electronic atlas of

    hematology [CD-ROM]. Philadelphia: Lippincott Williams &Wilkins; 2002.

    xii

    Pediatri Jan-Feb 08 15-02-08 11:00 12

  • xiii

    IV. O O :

    Abood S. Quality improvement initiative in nursing homes:the ANA acts in an advisory role. Am J Nurs [Internet]. 2002 Jun:Webpage:http://www.nursingworld.org/AJN/2002/june/Wawatch.htm

    :Foley KM, Gelband H, editors. Improving palliative care for

    cancer [Monograph, Internet]. Washington: National AcademyPress; 2001. Webpage: http://www.nap.edu/books/0309074029/html

    :Cancer-Pain.org [Webpage, Internet]. New York: Association

    of Cancer Online Resources, Inc.; 2002: http://www.cancer-pain.org/

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    Pediatri Jan-Feb 08 15-02-08 11:00 13

  • xiv ABBREVIATIONS

    Ao

    angstrom angstromcal caloriecm centimetercm2 square centimetercm3 cubic centimeteroC degree Celsiusg gramh hourIU international unitkg kilograml literm metermg milligrammin minutemm millimetermol molen numberNS not significantosm osmolep probabilitySD standard deviationSE standard errorsec secondU unit

    Combining prefixes

    tera- (1012) Tgiga- (109) Gmega- (106) Mkilo- (103) khector- (102) hdeca- (101) dadeci- (10-1) dcenti- (10-2) cmilli- (10-3) mmicro- (10-6) nano- (10-9) npico- (10-12) pfemto- (10-15) fatto- (10-18) a

    Pediatri Jan-Feb 08 15-02-08 11:00 14

  • xvINSTRUCTIONS TO AUTHORS

    A. General InformationThe Greek Paediatric Society is the owner of Paediatri-

    ki, its official scientific journal, which is distributed to itsmembers. Its objectives are the publication of paediatricscientific work and the continuing education of paediatri-cians. For this purpose, it publishes a variety of articles, andin particular:

    1. Editorials (upon invitation by the Editorial Board).2. Review articles.3. Award-winning articles.4. Original articles.5. Clinical Quiz.6. Round tables.7. Current issues.8. Issues of healthcare management and education.9. Case reports.

    10. News.11. Brief reports.12. Letters to the editor.13. Abstracts.14. Future congresses and events.15. Book reviews.

    The Editorial Board reserves the right to publish articlesof special scientific interest and articles on current issueswithout observing submission order. In addition, it publish-es upon decision original papers presented at the AnnualPaediatric Conference, presentations of special interest - inwhole or in part, and letters - in whole or in part - referringto scientific articles published in the journal.

    Regarding papers on current issues, the authors requestfor immediate publication should be quoted on the firstpage. The Editorial Board reserves the right to accept suchpapers for immediate publication.

    All manuscripts should not have been published previ-ously, in whole or in part, and not be under considerationby another publication. Manuscripts should acknowledgeany funding, sponsorship or other financial support. Allclinical research should have been conducted following in-formed consent of participants or of their legal representa-tives according to the Declarations of Helsinki and Tokyo.In addition, the US National Institute of Health guide forthe care and use of laboratory animals (DHEW Publication,NIH, 80-23) should have been observed. Clinical trialsshould have been approved by the Ethics Committee of theHospital.

    Authors opinions and conclusions expressed in the pub-lished papers do not necessarily reflect those of the journal.The Greek Paediatric Society, the Editorial Board and thePublisher of the journal do not necessarily approve the con-tent of the advertisements appearing in the journal.

    The copyright of all published papers is held by Paedia-triki and their reproduction in whole or in part is autho-rized only following written consent of the journal.

    B. Manuscript PreparationPaediatriki suggests compliance with the Uniform

    Requirements for Manuscripts Submitted to BiomedicalJournals, recently modified and published on the web-sites: http://www.icmje.org and http://www.icmje.org/icmje.pdf

    The entire paper (including figure legends and tables)

    should be typed on one side of blank paper format A4(21x29.7 cm), double line spacing and minimum indent 2.5cm on both sides.

    The paper should have the following structure: title page,short title, abstract in Greek and English, list of abbrevia-tions, text, acknowledgements and quoting of grants, spon-sorships or other financial support sources, references, ta-bles, figures, figure legends. Each of these sections should bestarted on a new page. Pages should be numbered consecu-tively, beginning with the title page.

    Text length shall be: review articles 2000-3000 words; original articles 1500-2500 words and case reports

    1000-1500 words; brief reports 1000-1500 words; letters 250-500 words.

    The title page should include: the title (

  • xvi

    Units of measures of laboratory analysesLaboratory analyses should be expressed in the Systme In-

    ternational (SI) units and in the metric (Conventional)...

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