Bacterial Infection (แพทย์)

  • Published on
    20-Aug-2015

  • View
    4.306

  • Download
    0

Embed Size (px)

Transcript

<ol><li> 1. Ratirath Samol, MD. BACTERIAL DISEASE RATIRATH SAMOL,MD </li><li> 2. Content <ul><li>Pyogenic gram positive cocci </li></ul><ul><li>Bacterial infection of childhood </li></ul><ul><li>Sexually transmitted bacterial disease </li></ul><ul><li>Enteropathogenic bacteria </li></ul><ul><li>Clostridial infection </li></ul><ul><li>Bacterial infection with animal reservoirs or insect vectors </li></ul><ul><li>Bacterial infection with immunocompromised host </li></ul><ul><li>Filamentous bacteria </li></ul><ul><li>Mycobacterial infection </li></ul><ul><li>Clamydia infection </li></ul><ul><li>Mycoplasma infection </li></ul><ul><li>Rickettsia infection </li></ul></li><li> 3. Pyogenic gram positive cocci </li><li> 4. Pyogenic gram positive cocci <ul><li>Staphylococcal infection </li></ul><ul><li>- coagulase positive (S. aureus) </li></ul><ul><li>- coagulase negative (S. epidermidis,</li></ul><ul><li>S. saprophyticus )</li></ul><ul><li>Streptococcal infection </li></ul><ul><li>- S. pyogenes </li></ul><ul><li>- S. agalactiae </li></ul><ul><li>- S. pneumoniae </li></ul><ul><li>- S. mutans </li></ul></li><li> 5. Staphylococcus spp. </li><li> 6. Streptococcus spp. </li><li> 7. Staphylococcus aureus <ul><li>Furuncles</li></ul><ul><li>- infection in and around hair follicles </li></ul><ul><li>- common in scalp, face, axillary </li></ul><ul><li>Carbuncles </li></ul><ul><li>- infection around hair follicle and produce </li></ul><ul><li>draining sinuses </li></ul><ul><li>Hydradenitis suppurativa </li></ul><ul><li>- infection in sweat gland </li></ul></li><li> 8. carbuncles furuncles </li><li> 9. Staphylococcus aureus <ul><li>Osteomyelitis </li></ul><ul><li>- infection in bone </li></ul><ul><li>Toxic shock syndrome (TSS) </li></ul><ul><li>- infection in surgical wound, tampons produce high fever, nausea, vomiting and shock </li></ul></li><li> 10. Staphylococcus aureus <ul><li>Food poisoning </li></ul><ul><li>- diarrhea, nausea, vomiting</li></ul><ul><li>- symptom present &lt; 6 hours after</li></ul><ul><li>contaminated food </li></ul></li><li> 11. Staphylococcus aureus <ul><li>Staphylocoocal scalded skin syndrome (SSSS) </li></ul><ul><li>- severe skin infection </li></ul><ul><li>- organism produce exfoliatin that destroys </li></ul><ul><li>desmogelin-1 (granulosa) of epidermis </li></ul><ul><li>bullae, rupture, skin scald </li></ul><ul><li>- other organs : lung, heart valve, bone </li></ul></li><li> 12. SSSS </li><li> 14. Staphylococcus epidermidis <ul><li>causes opportunistic infections in catheterized patients, patients with prosthetic cardiac valves, and drug addicts.</li></ul></li><li> 15. Staphylococcus saprophyticus <ul><li>common cause of urinary tract infections in young women. </li></ul></li><li> 16. Streptococcal infection<ul><li>3 types </li></ul><ul><li>-hemolytic streptococci </li></ul><ul><li>eg. S. pneumoniae, S. viridans, S. mutans </li></ul><ul><li>-hemolytic streptococci </li></ul><ul><li>eg. S. pyogenes (group A), S. agalactiae (group B) </li></ul><ul><li>-hemolytic streptococci (non-hemolytic) </li></ul><ul><li>eg. S. faecalis (group D) </li></ul></li><li> 17. -hemolytic streptococci <ul><li>S. pneumoniaeis a common cause of community-acquired pneumonia and meningitis in adults</li></ul><ul><li>S. viridansare part of the normal oral flora but are also a common cause of endocarditis</li></ul><ul><li>S. mutansis the major cause of dental caries </li></ul></li><li> 18. -hemolytic streptococci <ul><li>S. pyogenes (group A) </li></ul><ul><li>- pharyngitis </li></ul><ul><li>- scarlet fever </li></ul><ul><li>- erysipelas </li></ul><ul><li>- impetigo </li></ul><ul><li>- cellulitis </li></ul></li><li> 19. Pharyngitis <ul><li>Infection in throat (tonsillitis) </li></ul><ul><li>Clinical: high grade fever, sore throat </li></ul><ul><li>Complication :</li></ul><ul><li>- glomerulonephritis, rheumatic fever </li></ul><ul><li>- cross reaction of immune system to M </li></ul><ul><li>protein of bacteria </li></ul></li><li> 20. Tonsillitis </li><li> 21. Scarlet fever <ul><li>Common in childhood </li></ul><ul><li>Erythematous rash at trunk, extremities and faceexceptaround the mouth (circumoral pallor), strawberry tongue </li></ul><ul><li>Cause by erythrogenic toxin </li></ul></li><li> 22. Scarlet fever strawberry tongue circumoral pallor </li><li> 23. Erysipelas <ul><li>Erythematous rash, rapid distribution at face, particullary both cheek</li></ul><ul><li>Rash at trunk, extremities (uncommon) </li></ul></li><li> 24. Erysipelas </li><li> 25. Impetigo <ul><li>Infection in epidermis </li></ul><ul><li>Erythematous papulepustule </li></ul><ul><li>May be caused by S. pyogenes or S. aureus </li></ul></li><li> 26. Cellulitis <ul><li>Infection in deep dermis</li></ul><ul><li>S. pyogenes invade through wound </li></ul><ul><li>Pustule in deep dermis </li></ul><ul><li>Clinical : fever, erythematous skin lesion </li></ul></li><li> 27. Cellulitis </li><li> 28. -hemolytic streptococci <ul><li>S. agalactiae (group B) </li></ul><ul><li>- meningitis </li></ul><ul><li>- chorioamnionitis </li></ul><ul><li>- septicemia </li></ul></li><li> 29. Bacterial infection of childhood </li><li> 30. Bacterial infection of childhood <ul><li>Diphtheria </li></ul><ul><li>Pertussis (Whooping cough) </li></ul><ul><li>Haemophilus influenzae infection </li></ul><ul><li>Neisseria meningitidis infection </li></ul></li><li> 31. Diphtheria <ul><li>Caused by Corynebacterium diphtheriae (gram positive bacilli) </li></ul><ul><li>Transmitted as respiration </li></ul><ul><li>Immunization with diphtheria toxoid (formalin-fixed toxin) does not prevent colonization withC. diphtheriaebut protects immunized people from the lethal effects of the toxin. </li></ul></li><li> 32. Diphtheria <ul><li>Tracheal colonization may lead to </li></ul><ul><li>- Mucosal erosion </li></ul><ul><li>- Formation of a suffocating</li></ul><ul><li>pharyngeal fibrinosuppurative exudate</li></ul><ul><li>(pseudomembrane)obstruct airway </li></ul><ul><li>Toxin-mediated damage to the heart, nerves, liver, or kidneys </li></ul><ul><li>Microscopic: necrotic tissue, neutrophil, fibrin, bacteria </li></ul></li><li> 33. Diphtheria </li><li> 34. Pertussis <ul><li>Bordetella pertussis infection(gram negative coccobacilli ) </li></ul><ul><li>Common in childhood (</li></ul></li></ol>